Jan Rusz
Member of the Signal Analysis, Modelling, and Interpretation group
Department of Circuit Theory
Faculty of Electrical Engineering
Czech Technical University in Prague
Technicka 2, 166 27 Prague 6, Czech Republic

Tel: +420 224 352 287
Fax: +420 233 339 805
Email: ruszjan@fel.cvut.cz

Research Areas

  • Motor speech disorders
  • Movement disorders
  • Digital signal processing
  • Data analysis

    Google scholar: [link]

    Education

  • 2012 PhD degree in Electrical Engineering Theory, Faculty of Electrical Engineering, Czech Technical University
  • 2008 Ing. degree (MSc) with honnors in Biomedical Engineering, Faculty of Electrical Engineering, Czech Technical University

    Position

  • (2019-) Associate Professor at Faculty of Electrical Engineering of the Czech Technical University
  • (2008-) Researcher at the 1st Faculty of Medicine of the Charles University in Prague

    Peer-reviewed Journal Papers

    100. Barbe M, Rusz J, Simonyan K. Responsive deep brain stimulation: A new hope for controlling stimulation-induced dysarthria in essential tremor. Mov Disord 2024; in press.

    99. Tröger J, Dörr F, Schwed L, Linz N, König A, Thies T, Orozco-Arroyave JR, Rusz J. An Automatic Measure for Speech Intelligibility in Dysarthrias—Validation across Multiple Languages and Neurological Disorders. Front Digit Health 2024; 6:1440986. [PDF]

    98. Illner V, Novotný M, Kouba T, Tykalová T, Šimek M, Sovka P, Švihlík J, Růžička E, Šonka K, Dušek P, Rusz J. Smartphone voice calls provide early biomarkers of parkinsonism in REM sleep behaviour disorder. Mov Disord 2024; in press. [PDF]

    97. Holly P, Hubena T, Cihak M, Pavlikova A, Kemlink D, Ulmanova O, Rusz J, Jech R, Krupicka R, Ruzicka E. Estimating disability in patients with essential tremor: comparison of tremor rating scale, spiral drawing, and accelerometric tremor power. Mov Disord Clin Pract 2024; in press. [PDF]

    96. Rios Urrego CD, Rusz J, Orozco-Arroyave JR. Automatic speech-based assessment to discriminate Parkinson’s disease from essential tremor with a cross-language approach. NPJ Dig Med 2024; 7:37. [PDF]

    95. Šubert M, Novotný M, Tykalová T, Hlavnička J, Dušek P, Růžička E, Škrabal D, Pelletier A, Postuma RB, Montplaisir J, Gagnon JF, Galbiati A, Ferini-Strambi L, Marelli S, St Louis EK, Timm PC, Teigen LN, Janzen A, Oertel W, Heim B, Holzknecht E, Stefani A, Högl B, Dauvilliers Y, Evangelista E, Šonka K, Rusz J. Spoken Language Alterations can Predict Phenoconversion in Isolated rapid eye movement Sleep Behavior Disorder: A Multicentric Study. Ann Neurol 2024; in press. [PDF]

    94. Holly P, Duspivova T, Kemlink D, Ulmanova O, Rusz J, Krupicka R, Jech R, Ruzicka E. Essential and dystonic head tremor: more similarities than differences. Park Relat Disord 2023; 115:105850. [PDF]

    93. Subert M, Novotny M, Tykalova T, Srpova B, Friedova L, Uher T, Horakova D, Rusz J. Lexical and Syntactic Deficits Analyzed via Automated Natural Language Processing: The New Monitoring Tool in Multiple Sclerosis. Ther Adv Neurol Disord 2023; 16:1-13. [PDF]

    92. Cmejla R, Novotny M, Rusz J, Tykalova T, Vimr J, Hlavnicka J. The automated screening of speech motor development in children based on the sequential motion rate. Comp Biol Med 2023; 162:107086. [PDF]

    91. Illner V, Tykalova T, Skrabal D, Klempir J, Rusz J. Automated Vowel Articulation Analysis in Connected Speech Among Progressive Neurological Diseases, Dysarthria Types, and Dysarthria Severities. J Speech Lang Hear Res 2023; 66:2600-2621. [PDF]

    90. Boogers A, Peeters J, Van Bogaert T, Rusz J, Bogaert-Miclaus C, Loret G, De Vloo P, Vandenberghe W, Nuttin B, Mc Laughlin M. Acute stimulation with symmetric biphasic pulses induces less ataxia compared to cathodic pulses in DBS for essential tremor. Park Relat Disord 2023; 111:105435. [PDF]

    89. Rusz J, Krupicka E, Viteckova S, Tykalova T, Novotny M, Novak J, Dusek P, Ruzicka E. Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease. CNS Neurosci Rehab 2023; 29:2101-2110. [PDF]

    88. Kouba T, Frank W, Tykalova T, Mühlbäck A, Klempíř J, Lindenberg KS, Landwehrmeyer GB, Rusz J. Speech biomarkers in Huntington disease: a cross-sectional study in pre-symptomatic, prodromal and early manifest stages. Eur J Neurol 2023;30:1262-1271. [PDF]

    87. Svihlik J, Novotny M, Tykalova T, Polakova K, Brozova H, Kryze P, Sousa M, Krack P, Tripoliti E, Ruzicka E, Jech R, Rusz J. Long-Term Averaged Spectrum Descriptors of Dysarthria in Patients With Parkinson’s Disease Treated With Subthalamic Nucleus Deep Brain Stimulation. J Speech Lang Hear Res 2022;65:4690-4699. [PDF]

    86. Daoudi K, Biswajit D, Tykalova T, Klempir J, Rusz J. Speech acoustic indices for differential diagnosis between Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy. NPJ Parkinsons Dis 2022;8:142. [PDF]

    85. Skrabal D, Rusz J, Novotny M, Ruzicka E, Dusek P, Tykalova T. Articulatory undershoot of vowels in isolated REM sleep behavior disorder and early Parkinson’s disease. NPJ Parkinsons Dis 2022;8:137. [PDF]

    84. Novotny M, Tykalova T, Ruzickova H, Ruzicka E, Dusek P, Rusz J. Automated video-based assessment of facial bradykinesia in de-novo Parkinson’s disease. NPJ Dig Med 2022;98. [PDF]

    83. Svoboda E, Boril T, Rusz J, Tykalova T, Horakova D, Guttmann CRG, Blagoev KB, Hatabu H, Valtchinov VI. Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study. Comp Biol Med 2022;148:105853. [PDF]

    82. Subert M, Simek M, Novotny M, Tykalova T, Bezdicek O, Ruzicka E, Sonka K, Dusek P, Rusz J. Linguistic abnormalities in isolated rapid eye movement sleep behavior disorder. Mov Disord 2022;37:1872-1882. [PDF]

    81. Kouba T, Illner V, Rusz J. Study protocol for using a smartphone application to investigate speech biomarkers of Parkinson’s disease and other synucleinopathies: SMARTSPEECH. BMJ Open 2022; 12:e059871. [PDF]

    80. Holly P, Duspivova T, Kemlink D, Ulmanova O, Rusz J, Krupicka J, Jech R, Ruzicka E. Práh pro somatosenzorickou časovou diskriminaci nediferencuje mezi pacienty s esenciálním a dystonickým třesem hlavy. Cesk Slov Neurol N 2022;85/118:163-167. [PDF]

    79. Viteckova S, Rusz J, Ruzicka E, Krupicka R. Is Gait Dysfunction Prominent Sign of Isolated Rapid Eye Movement Sleep Behavior Disorder? Mov Disord 2022;37:1575-1576. [PDF]

    78. Tykalova T, Novotny M, Ruzicka E, Dusek P, Rusz J. Short-term effect of dopaminergic medication on speech in early-stage Parkinson's disease. NPJ Parkinsons Dis 2022; 8:22. [PDF]

    77. Ganapathy R, Levová K, Kotačková L, Trnka J, Zogala D, Rusz J, Zima T, Devos D, Šonka K, Růžička E, Kalousová M, Dušek. Increased transferrin sialylation predicts phenoconversion in isolated REM sleep behavior disorder. Mov Disord 2022; 37:983-992. [PDF]

    76. Illner V, Tykalova T, Novotny M, Klempir J, Dusek P, Rusz J. Towards automated articulation rate analysis via connected speech in dysarthrias. J Speech Lang Hear Res; 2022;65:1386-1401. [PDF]

    75. Šimek M, Rusz J. Validation of cepstral peak prominence in assessing early voice changes of Parkinson’s disease: effect of speaking task and ambient noise. J Acoust Soc Am 2021; 150:4522-4533. [PDF]

    74. Rusz J, Tykalova T. Does Cognitive Impairment Influence Motor Speech Performance in De Novo Parkinson's Disease? Mov Disord 2021; 36:2980-2982. [PDF]

    73. Rusz J, Janzen A, Tykalova T, Novotny M, Zogala D, Timmermann L, Růžička E, Šonka K, Dušek P, Oertel W. Dysprosody in Isolated REM Sleep Behavior Disorder with Impaired Olfaction but Intact Nigrostriatal Pathway. Mov Disord 2022; 37:619-623. [PDF]

    72. Rusz J, Tykalova T, Novotny M, Růžička E, Dušek P. Distinct patterns of speech disorder in early-onset and late-onset de-novo Parkinson’s disease. NPJ Parkinsons Dis 2021; 7:98. [PDF]

    71. Rusz J, Tykalova T, Novotny M, Zogala D, Šonka K, Růžička E, Dušek P. Defining speech subtypes in de novo Parkinson's disease: response to long-term levodopa therapy. Neurology 2021; 97:e2124-e2135. [PDF]

    70. Rusz J, Tykalova T, Novotny M, Zogala D, Růžička E, Dušek P. Automated speech analysis in early untreated Parkinson's disease: relation to gender and dopaminergic transporter imaging. Eur J Neurol 2021; 29:81-90. [PDF]

    69. Miglis MG, Adler CH, Antelmi E, Arnaldi D, Baldelli L, Boeve BF, Cesari M, Dall’Antonia I, Diederich NJ, Doppler K, Dušek P, Ferri R, Gagnon J-F, Gan-Or Z, Hermann W, Högl B, Hu MT, Iranzo A, Janzen A, Kuzkina A, Lee J-Y, Leenders KL, Lewis SJG, Liguori C, Liu J, Lo C, Ehgoetz Martens KA, Nepozitek J, Plazzi G, Provini F, Puligheddu M, Rolinski M, Rusz J, Stefani A, Summers RLS, Yoo D, Zitser J, Oertel WH. Biomarkers of conversion to alpha-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder. Lancet Neurol 2021;20:671-684. [PDF]

    68. Kryze P, Tykalova T, Ruzicka E, Rusz J. Effect of reading passage length on quantitative acoustic speech assessment in Czech-speaking individuals with Parkinson’s disease treated with subthalamic nucleus deep brain stimulation. J Acoust Soc Am 2021;3366-3374. [PDF]

    67. Rusz J, Svihlik J, Kryze P, Novotny M, Tykalova T. Reproducibility of Voice Analysis with Machine Learning. Mov Disord 2021; 36:1282-1283. [PDF]

    66. Rusz J, Hlavnicka J, Novotny M, Tykalova T<, Pelletier A, Montplaisir J, Gagnon J-F, Dusek P, Galbiati A, Marelli S, Timm PC, Teigen LN, Janzen A, Habibi M, Stefani A, Holzknecht E, Seppi K, Evangelista E, Rassu AL, Dauvilliers Y, Hogl B, Oertel W, St Louis EK, Ferini-Strambi L, Ruzicka E, Postuma RB, Sonka K. Speech biomarkers in rapid eye movement sleep behaviour disorder and Parkinson's disease. Ann Neurol 2021; 90:62-75. [PDF]

    65. Vasquez-Correa JC, Rios-Urrego CD, Arias-Vergara T, Schuster M, Rusz J, Nöth E, Orozco-Arroyave JR. Transfer Learning Helps to Improve the Accuracy to Classify Patients with Different Speech Disorders in Different Languages. Pattern Recognit Lett 2021; 150:272-279. [PDF]

    64. Rusz J, Tykalova T, Ramig LO, Tripoliti E. Reply to: “Fostering Voice Objective Analysis in Patients With Movement Disorders”. Mov Disord 2021; 36:1042-1043. [PDF]

    63. Rusz J, Tykalova T, Ramig LO, Tripoliti E. Guidelines for speech recording and acoustic analyses in dysarthrias of movement disorders. Mov Disord 2021; 36:230-238. [PDF]

    62. Polakova K, Ruzicka E, Jech R, Kemlink D, Rusz J, Miletinova E, Brozova H. 3D visual cueing shortens the double support phase of the gait cycle in patients with advanced Parkinson’s disease treated with DBS of the STN. PLoS ONE 2020; 15(12): e0244676. [PDF]

    61. E. Eyigoz, M. Courson, L. Sedeno, K. Rogg, J.R. Orozco-Arroyave, E. Noth, S. Skodda, N. Trujillo, M. Rodriguez, J. Rusz, E. Munoz, J.F. Cardona, E. Herrera, E. Hesse, A. Ibanez, G. Cecchi, A.M. Garcia. (2020). "From discourse to pathology: Automatic identification of Parkinson's disease patients via morphological measures across three languages," Cortex, 132 (November): 191-205. [PDF]

    60. J. Rusz, and T. Tykalová. (2020). "Reader response: Motor speech patterns in Huntington disease," Neurology, 95 (13 September). [PDF]

    59. M. Novotny, J. Melechovsky, K. Rozenstoks, T. Tykalova, P. Kryze, M. Kanok, J. Klempir, and J. Rusz. (2020). "Comparison of Automated Acoustic Methods for Oral Diadochokinesis Assessment in Amyotrophic Lateral Sclerosis," Journal of Speech, Language and Hearing Research, 63 (10 November): 3453-3460. [PDF]

    58. T. Tykalová, J. Rusz, J. Švihlík. S. Bancone, A. Spezia, and M. T. Pellecchia. (2020). "Speech disorder and vocal tremor in postural instability/gait difficulty and tremor dominant subtypes of Parkinson’s disease," Journal of Neural Transmission, 127 (9 September): 1295-1304. [PDF]

    57. R. Krupička, P. Krýže, S. Neťuková, T. Duspivová, O. Klempíř, Z. Szabó, P. Dušek, K. Šonka, J. Rusz, E. Růžička. Instrumental analysis of finger tapping reveals a novel early biomarker of parkinsonism in idiopathic rapid eye movement sleep behaviour disorder," Sleep Medicine, 75 (November): 45-49. [PDF]

    56. T. Tykalová, D. Škrabal, T. Bořil, R. Čmejla, J. Volín, and J. Rusz. (2020). "Effect of aging on acoustic characteristics of voice pitch and formants in Czech vowels," Journal of Voice 2021; 931.e21-931.e33. [PDF]

    55. D. Škrabal, T. Tykalová, J. Klempíř, E. Růžička, and J. Rusz. (2020). "Dysarthria enhancement mechanism under external clear speech instruction in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy," Journal of Neural Transmission, 127 (6 June): 905-914. [PDF]

    54. J. Hanuška, J. Rusz, O. Bezdíček, P. Dušek, K. Šonka, and E. Růžička. (2020). "Comment on “pro-saccades predict cognitive decline in Parkinson's disease: ICICLE-PD”," Movement Disorders, 35(3 March):522. [PDF]

    53. J. Hlavnička, T. Tykalová, O. Ulmanová, P. Dušek, D. Horáková, J. Klempíř, and J. Rusz. (2020). "Characterizing vocal tremor in progressive neurological diseases via automated acoustic analyses," Clinical Neurophysiology, 131(5 May): 1155-1165. [PDF] [Editorial]

    52. S. Vítečková, J. Rusz, R. Krupička, P. Dušek, and E. Růžička. (2020)."Instrumental Analysis of Gait Abnormalities in Idiopathic Rapid Eye Movement Sleep Behavior Disorder," Movement Disorders, 35(1 January):193-195. [PDF]

    51. V. Illner, P. Sovka, J.Rusz. (2020). "Validation of freely-available pitch detection algorithms across various noise levels in assessing speech captured by smartphone in Parkinson’s disease," Biomedical Signal Processing and Control, 58(April): 101831. [PDF]

    50. J. Hanuška, P. Dušek, J. Rusz, O. Ulmanová, A. Burgetová, and E. Růžička. (2020). "Eye movement abnormalities are associated with brainstem atrophy in Wilson disease," Neurological Sciences, 41(5 May): 1097-1103. [PDF]

    49. M. Novotný, P. Dušek, I. Daly, E. Růžička, J.Rusz. (2020)."Glottal Source Analysis of Voice Deficits in Newly Diagnosed Drug-naive Patients with Parkinson’s Disease: Correlation Between Acoustic Speech Characteristics and Non-Speech Motor Performance," Biomedical Signal Processing and Control, 57(March): 101818. [PDF]

    48. P. Dušek, V. Ibarburu Lorenzo y Losada, O. Bezdíček, I. Dall’Antonia, S. Dostálová, P. Kovalská, R. Krupička, J. Nepožitek, T. Nikolai, M. Novotný, P. Peřinová, J. Rusz, T. Serranová, T.Tykalová, O. Ulmanová, Z. Mecková, V. Ptáčník, J. Trnka, D. Zogala, E. Růžička, and K. Šonka. (2019)."Relations of non-motor symptoms and dopamine transporter binding in REM sleep behavior disorder," Scientific Reports, 9(October): 15463. [PDF]

    47. J. Hlavnička, R. Čmejla, J. Klempíř, E. Růžička, and J. Rusz. (2019)."Acoustic tracking of pitch, modal and subharmonic vibrations of vocal folds in Parkinson's disease and Parkinsonism," IEEE Access, 7(December): 150339-150354. [PDF]

    46. K. Rozenstoks, M. Novotný, D. Horáková, J. Rusz. (2020)."Automated assessment of oral diadochokinesis in multiple sclerosis using a neural network approach: effect of different syllable repetition paradigms," IEEE Transactions on Neural Systems and Rehabilitation Engineering, 28(January): 32-41. [PDF]

    45. K. Novotná, J. Rusz, E. Kubala Havrdová, J. Lízrová Preiningerová. (2019). "Why patients with multiple sclerosis perceive improvement of gait during treatment with natalizumab?," Journal of Neural Transmission, 126(6 June): 731-737. [PDF] [cited]

    44. J. Rusz, M. Vaněčková, B. Beňová, T. Tykalová, M. Novotný, H. Růžičková, T. Uher, M. Andělová, K. Novotná, L. Friedová, J. Motýl, K. Kučerová, J. Krásenský, D. Horáková. (2019). "Brain volumetric correlates of dysarthria in multiple sclerosis," Brain and Language, 194(7 June): 58-64. [PDF]

    43. L. Friedová, J. Rusz, J. Motýl, B. Srpová, K. Vodehnalová, M. Andělová, K. Novotná, M. Novotný, H. Růžičková, T. Tykalová, E. K. Havrdová, D. Horáková, and T. Uher. (2019). "Slowed articulation rate is associated with information processing speed decline in multiple sclerosis: A pilot study," Journal of Clinical Neuroscience, 65(7 July): 28-33. [PDF]

    42. L. Brabcová, J. Roth, O. Ulmanová, J. Rusz, J. Klempíř, O. Horáček, M. Kolářová, P. Kosková, P. Rolková, H. Božková, L. Sabó, M. Inemanová, K. Lísalová, F. Jančok, E. Růžička, and H. Brožová. (2019)."Inpatient multidisciplinary rehabilitation program for postural and gait stability in Huntington´s disease – a pilot study," Česká a slovenská neurologie a neurochirurgie, 82/115(5-6 May): 301-308. [PDF]

    41. J. Rusz, T. Tykalová, G. Salerno, S. Bancone, J. Scarpelli, M. T. Pellecchia. (2019). "Distinctive speech signature in cerebellar and parkinsonian subtypes of multiple system atrophy," Journal of Neurology, 266(6 June): 1394-1404. [PDF] [cited]

    40. J. Rusz, A. Fečíková, T. Tykalová, R. Jech. (2019). "Effect of pallidal deep-brain stimulation on articulation rate in dystonia," Neurological Sciences, 27(March): 440–449. [PDF]

    39. L. Moro-Velazquez, J. A. Gomez-Garcia, J. I. Godino-Llorente, J. Villalba, J. Rusz, S. Shattuck-Hufnagel, N. Dehak. (2019). "A forced gaussians based methodology for the differential evaluation on Parkinson's disease by means of speech processing," Biomedical Signal Processing and Control (February), 48: 205-220. [PDF] [cited]

    38. J. Rusz, J. Hlavnička, T. Tykalová, M. Novotný, P. Dušek, K. Šonka, and E. Růžička. (2018). "Smartphone allows capture of speech abnormalities associated with high risk of developing Parkinson’s disease," IEEE Transactions on Neural Systems and Rehabilitation Engineering, 26(8 August): 1495-1507. [PDF] [cited]

    37. J. Hanuška, J. Rusz, O. Bezdíček, O. Ulmanová, C. Bonnet, P. Dušek, V. Ibarburu, T. Nikolai, T. Sieger, K. Šonka, and E. Růžička. (2019). "Eye Movements in Idiopathic REM Sleep Behavior Disorder: High Antisaccade Error Rate Reflects Prefrontal Cortex Dysfunction," Journal of Sleep Research, 28(October):e12742. [PDF] [cited]

    36. M. Skorvanek, E. Feketeova, M. M. Kurtis, J. Rusz, and K. Šonka. (2018). "Accuracy of rating scales and clinical measures for screening of rapid eye movement sleep behavior disorder and for predicting conversion to Parkinson’s disease and other synucleinopathies," Frontiers in Neurology, 9: 376. [PDF] [cited]

    35. J. Rusz, T. Tykalová, A. Fečíková, D. Šťastná, D. Urgošík, R. Jech. (2018). "Dualistic effect of pallidal deep brain stimulation on motor speech disorders in dystonia," Brain Stimulation, 11(4 July-August): 896-903. [PDF] [cited]

    34. J. Rusz, B. Beňová, H. Růžičková, M. Novotný, T. Tykalová, J. Hlavnička, T. Uher, M. Vaněčková, M. Andělová, K. Novotná, L. Kadrnožková, and D. Horáková. (2018). "Characteristics of motor speech phenotypes in multiple sclerosis," Multiple Sclerosis and Related Disorders, 19(1 January): 62-69. [PDF] [cited]

    33. C. Bonnet, J. Rusz, J. Hanuška, M. Dezortová, F. Jírů, T. Sieger, R. Jech, J. Klempíř, J. Roth, O. Bezdíček, T. Serranová, P. Dušek, T. Uher, C. Flammand-Roze, M. Hájek, and E. Růžička (2017). GABA spectra and remote distractor effect in progressive supranuclear palsy: A pilot study. Revue Neurologique, 173(4 April): 225-229. [PDF] [cited]

    32. J. Hlavnička, R. Čmejla, T. Tykalová, K. Šonka, E. Růžička, and J. Rusz (2017). "Automated analysis of connected speech reveals early biomarkers of Parkinson’s disease in patients with rapid eye movement sleep behaviour disorder," Scientific Reports, 7: 12. [PDF] [cited]

    31. J. Rusz, T. Tykalová, R. Krupička, K. Zárubová, M. Novotný, R. Jech, Z. Szabó, and E. Růžička. (2017). "Comparative analysis of speech impairment and upper limb motor dysfunction in Parkinson’s disease," Journal of Neural Transmission, 124(4 April): 463-470. [PDF] [cited]

    30. T. Tykalová, J. Rusz, J. Klempíř, R. Čmejla, and E. Růžička. (2017). "Distinct patterns of consonant articulation among Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy," Brain and Language, 165(2 February): 1-9. [PDF] [cited]

    29. J. Rusz, M. Novotný, J. Hlavnička, T. Tykalová, and E. Růžička. (2017). High-accuracy voice-based classification between patients with Parkinson’s disease and other neurological diseases may be an easy task with inappropriate experimental design. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 25(8 August): 1319-1321. [PDF] [cited]

    28. M. Novotný, J. Rusz, R. Čmejla, H. Růžičková, J. Klempíř, and E. Růžička. (2016). "Hypernasality associated with basal ganglia dysfunction: evidence from Parkinson’s disease and Huntington’s disease," PeerJ, 4: 2530. [PDF] [suppl. material] [cited]

    27. A.M. Rulseh, J. Keller, J. Rusz, M. Syka, H. Brožová, R. Rusina, P. Havránková, K. Zárubová, H. Malíková, R. Jech, and J. Vymazal. (2016). "Diffusion tensor imaging in the characterization of multiple system atrophy," Neuropsychiatric Disease and Treatment, 12: 2181-2187. [PDF] [cited]

    26. E. Růžička, R. Krupička, K. Zárubová, J. Rusz, R. Jech, Z. Szabó. (2016). "Test of manual dexterity and speed in Parkinson’s disease: Not all measure the same," Parkinsonism & Related Disorders, 28(7): 118-123. [PDF] [cited]

    25. J. Rusz, T. Tykalová, J. Klempíř, R. Čmejla, and E. Růžička. (2016). "Effects of dopaminergic replacement therapy on motor speech disorders in Parkinson's disease: a longitudinal follow-up study on previously untreated patients," Journal of Neural Transmission, 123(4): 379-387. [PDF] [cited]

    24. J.R. Orozco-Arroyave, F. Honig, J.D. Arias-Londono, J.F. Vargas-Bonilla, K. Daqrouq, S. Skodda, J. Rusz, and E. Noth. (2016). "Automatic detection of Parkinson's disease in running speech spoken in three different languages," Journal of the Acoustical Society of America, 139(1): 481-500. [PDF] [cited]

    23. T. Tykalová, M. Pospíšilová, R. Čmejla, J. Jeřábek, P. Mareš, J. Rusz. (2016). "Speech changes after coordinative training in patients with cerebellar ataxia: A pilot study," Neurological Sciences, 37(2): 293-296. [PDF] [cited]

    22. J. Rusz, J. Hlavnička, T. Tykalová, J. Bušková, O. Ulmanová, E. Růžička and K. Šonka. (2015). "Quantitative assessment of motor speech abnormalities in idiopathic rapid eye movement sleep behaviour disorder," Sleep Medicine, 19(3): 141-147. [PDF] [cited]

    21. J.R. Orozco-Arroyave, E.A. Belalcazar-Bolanos, J.D. Arias-Londono, J.F. Vargas-Bonilla, S. Skodda, J. Rusz, K. Daqrouq, F. Honig, and E. Noth. (2015). "Characterization Methods for the Detection of Multiple Voice Disorders: Neurological, Functional, and Laryngeal Diseases," IEEE Journal of Biomedical and Health Informatics, 19(6): 1820-1828. [PDF] [cited]

    20. J. Rusz, J. Hlavnička, R. Čmejla, and E. Růžička. (2015). "Automatic evaluation of speech rhythm instability and acceleration in dysarthrias associated with basal ganglia dysfunction," Frontiers in Bioengineering and Biotechnology, 3:104. [PDF] [cited]

    19. J. Hanuška, C. Bonnet, J. Rusz, T. Sieger, R. Jech, S. Rivaud-Péchoux, M. Vidailhet, B. Gaymard, and E. Růžička. (2015). "Fast Vergence Eye Movements Are Disrupted in Parkinson's Disease: A Video-oculography Study" Parkinsonism & Related Disorders, 21(7): 797-799. [PDF] [cited]

    18. J. Rusz, C. Bonnet, J. Klempíř, T. Tykalová, E. Baborová, M. Novotný, A. Rulseh, and E. Růžička. (2015). "Speech disorders reflect differing pathophysiology in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy," Journal of Neurology, 262(4): 992-1001. [PDF] [cited]

    17. J. Lízrová Preiningerová, K. Novotná, J. Rusz, L. Suchá, E. Růžička, and E. Havrdová. (2015). "Spatial and Temporal Characteristics of Gait as Outcome Measures in Multiple Sclerosis (EDSS 0 to 6.5)," Journal of NeuroEngineering and Rehabilitation, 12: 14. [PDF] [cited]

    16. T. Tykalová, J. Rusz, R. Čmejla, J. Klempíř, H. Růžičková, J. Roth, and E. Růžička. (2015). "Effect of dopaminergic medication on speech dysfluency in Parkinson's disease: a longitudinal study," Journal of Neural Transmission, 122(8 August): 1135-1142. [PDF] [cited]

    15. J. Rusz, C. Saft, U. Schlegel, R. Hoffman, S. Skodda. (2014). "Phonatory Dysfunction as a Preclinical Symptom of Huntington Disease," PLoS One, 9(11): e113412. [PDF] [cited]

    14. C. Bonnet, J. Rusz, M. Megrelishvili, T. Sieger, O. Matoušková, M. Okujava, H. Brožová, T. Nikolai, J. Hanuška, M. Kapianidze, N. Mikeladze, N. Botchorishvili, I. Khatiashvili, M. Janelidze, T. Serranová, O. Fiala, J. Roth, J. Bergquist, R. Jech, S. Rivaud-Péchoux, B. Gaymard, E. Růžička. (2014). "Eye Movements in Ephedrone-induced Parkinsonism," PLoS One, 9(8): e104784. [PDF] [cited]

    13. M. Novotný, J. Rusz, R. Čmejla, E. Růžička. (2014). Automatic evaluation of articulatory disorders in Parkinson's disease. IEEE/ACM Transactions on Audio, Speech, and Language Processing, 22(9): 1366-1378. [PDF] [cited]

    12. J. Rusz, J. Klempíř, T. Tykalová E. Baborová, R. Čmejla, E. Růžička, and J. Roth. (2014). "Characteristics and occurrence of speech impairment in Huntington's disease: possible influence of antipsychotic medication," Journal of Neural Transmission, 121(12): 655-664. [PDF] [cited]

    11. J. Rusz, M. Megrelishvili, C. Bonnet, M. Okujava, H. Brožová, I. Khatiashvili, M. Sekhniashvili, M. Janelidze, E. Tolosa, E. Růžička. (2014). "A distinct variant of mixed dysarthria reflects parkinsonism and dystonia due to ephedrone abuse," Journal of Neural Transmission, 121(6): 655-664. [PDF] [cited]

    10. T. Tykalová, J. Rusz, R. Čmejla, H. Růžičková, and E. Růžička. (2014). "Acoustic Investigation of Stress Patterns in Parkinson's Disease," Journal of Voice, 28(1): 129.e1-129.e8. [PDF] [cited]

    9. J. Rusz, R. Čmejla, T. Tykalová, H. Ružičková, Jiří Klempíř, Veronika Majerová, Jana Picmausová, Jan Roth, and E. Růžička. (2013). "Imprecise vowel articulation as a potential early marker of Parkinson’s disease: Effect of speaking task," Journal of the Acoustical Society of America, 134(3): 2171-2181. [PDF] [cited]

    8. J. Rusz, J. Klempíř, E. Baborová, T. Tykalová, V. Majerová, R. Čmejla, E. Růžička, and J. Roth. (2013). "Objective Acoustic Quantification of Phonatory Dysfunction in Huntington's Disease," PLoS One, 8(6): e65881. [PDF] [cited]

    7. C. Bonnet, J. Hanuška, J. Rusz, S. Rivaud-Péchoux, T. Sieger, V. Majerová, T. Serranová, B. Gaymard, and E. Růžička. (2013). "Horizontal and Vertical Eye Movement Metrics: What´s Important?" Clinical Neurophysiology, 124(11): 2216-2229. [PDF] [cited]

    6. J. Rusz, R. Čmejla, H. Ružičková, J. Klempíř, V. Majerová, J. Picmausová, J. Roth, and E. Růžička. (2013). "Evaluation of speech impairment in early stages of Parkinson's disease: a prospective study with the role of pharmacotherapy," Journal of Neural Transmission, 120(2): 319-329. [PDF] [cited]

    5. R. Čmejla, J. Rusz, P. Bergl, and J. Vokřál. (2013). Bayesian changepoint detection for the automatic assessment of fluency and articulatory disorders. Speech Communication, 55(1): 178-189. [PDF] [suppl. material] [cited]

    4. J. Rusz, R. Čmejla, H. Ružičková, J. Klempíř, V. Majerová, J. Picmausová, J. Roth, and E. Růžička. (2011). "Acoustic assessment of voice and speech disorders in Parkinson’s disease through quick vocal test," Movement Disorders, 26(10): 1951-1952. [PDF] [suppl. material] [cited]

    3. J. Kofránek, S. Matoušek, J. Rusz, P. Stodůlka, P. Privitzer, M. Mateják, and M. Tribula. (2011). "The Atlas of Physiology and Pathophysiology: Web-Based Multimedia Enabled Interactive Simulations," Computer Methods and Programs in Biomedicine, 104(2): 143-153. [PDF] [www] [cited]

    2. J. Rusz, R. Čmejla, H. Ružičková, and E. Růžička. (2011). "Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson’s disease," Journal of the Acoustical Society of America, 129(1): 350-367. [PDF] [cited]

    1. J. Kofránek, and J. Rusz. (2010). "Restoration of Guyton´s Diagram for Regulation of the Circulation as a Basis for Quantitative Physiological Model Development," Physiological Research, 59(6): 897-908. [PDF] [suppl. material] [cited]

    Selected Full Conference Papers

    12. B. Das, K. Daoudi, J. Klempíř, J. Rusz (2019). "Towards disease-specific markers for differential diagnosis of parkinsonism," in Proceedings of the IEEE Signal Processing Society, International Conference on Acoustics, Speech and Signal Processing (ICASSP), Brighton, UK, 2019, 5846-5850. [PDF]

    11. L. Moro-Velazquez, J. A. Gomez-Garcia, J. I. Godino-Llorente, J. Rusz, S. Skodda, F. Grandas, J. M. Velazquez, J. R. Orozco-Arroyave, E. Noth, N. Dehak. "Study of the automatic detection of Parkinson's disease based on speaker recognition technologies and allophonic distilation," in 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018, Honolulu, HI, 1404-1407. [PDF]

    10. G. Li, K. Daoudi, J. Klempíř, J. Rusz (2018). "Linear classification in speech-based objective differential diagnosis of parkinsonism," in Proceedings of the IEEE Signal Processing Society, International Conference on Acoustics, Speech and Signal Processing (ICASSP), Calgary, Alberta, Canada, 2018, 5999-6003. [PDF]

    9. M. Novotný, J. Rusz, K. Spálenka, J. Klempíř, D. Horáková, and E. Růžička. (2017). "Acoustic evaluation of nasality in cerebellar syndromes," in Proceedings of the 18th Annual Conference of the International Speech Communication Association (INTERSPEECH), Stockholm, Sweden, 2017, 3132-3136. [PDF]

    8. J. Hlavnička, T. Tykalová, R. Čmejla, J. Klempíř, E. Růžička, and J. Rusz. (2017). "Dysprosody differentiate between Parkinson’s disease, progressive supranuclear palsy, and multiple system atrophy" in Proceedings of the 18th Annual Conference of the International Speech Communication Association (INTERSPEECH), Stockholm, Sweden, 2017, 1844-1848. [PDF]

    7. J.R. Orozco-Arroyave, J.C. Vasquez-Correa, F. Honig, J.D. Arias-Londono, J.F. Vargas-Bonilla, S. Skodda, J. Rusz, and E. Noth. (2016). "Towards an automatic monitoring of the neurological state of Parkinson's patients from speech," in Proceedings of the IEEE Signal Processing Society, International Conference on Acoustics, Speech and Signal Processing (ICASSP), Shanghai, China, 2016, 6490-6494. [PDF] [cited]

    6. T. Tykalová, J. Hlavnička, M. Mačáková, M. Baxa, R. Čmejla, J. Motlík, J. Klempíř, J. Rusz. (2015). "Grunting in a Genetically Modified Minipig Animal Model for Huntington’s Disease – Pilot Experiments," Cesk Slov Neurol N, 78/111(Suppl 2): 2S61–2S65. [PDF]

    5. J.R. Orozco-Arroyave, F. Honig, J.D. Arias-Londono, J.F. Vargas-Bonilla, S. Skodda, J. Rusz, and E. Noth. (2015). "Voiced/unvoiced transitions in speech as a potential bio-marker to detect Parkinson’s disease," in Proceedings of the 16th Annual Conference of the International Speech Communication Association (INTERSPEECH), Dresden, Germany, 2015, 95-99. [PDF] [cited]

    4. M. Novotný, J. Pospíšil, R. Čmejla, J. Rusz (2015). "Automatic Detection of Voice Onset Time in Dysarthric Speech," in Proceedings of the IEEE Signal Processing Society, International Conference on Acoustics, Speech and Signal Processing (ICASSP), Brisbane, Australia, 2015, 4340-4344. [PDF] [cited]

    3. J.R. Orozco-Arroyave, F. Honig, J.D. Arias-Londono, J.F. Vargas-Bonilla, S. Skodda, J. Rusz, E. Noth (2014). "Automatic Detection of Parkinson’s Disease from Words Uttered in Three Different Languages," in Proceedings of the 15th Annual Conference of the International Speech Communication Association (INTERSPEECH), Singapore, Australia, 2014, 1573-1577. [PDF] [cited]

    2. T. Bocklet, E. Nöth, G. Stemmer, H. Ruzickova, and J. Rusz. (2011). "Detection of Persons with Parkinson’s Disease by Acoustic, Vocal, and Prosodic Analysis," in 2011 IEEE Automatic Speech Recognition and Understanding Workshop (Proc. of ASRU 2011), Big Island, Hawaii, USA, 478-483. [PDF] [cited]

    1. J. Kofránek, P. Privitzer, S. Matoušek, M. Mateják, O. Vacek, M. Tribula, and J. Rusz. (2009). "Schola ludus in modern garment: use of web multimedia simulation in biomedical teaching," in Proceedings of the 7th IFAC Symposium on Modeling and Control in Biomedical Systems," Aalborg, Denmark, 425-430. [PDF] [cited]

    Awards

  • 2023 Ministry of Health prize for the outstanding research project [Diploma]
  • 2022 2x CUNI Dean's Prize prize for the outstanding original research in 2021
  • 2022 Czech Neurological Society prize for excellent teaching text in 2021
  • 2022 CTU Rector's Prize for outstanding publication Speech biomarkers in rapid eye movement sleep behaviour disorder and Parkinson's disease
  • 2019 Czech Neurological Society prize for the outstanding original research in 2018
  • 2019 CUNI Dean's Prize prize for the outstanding original research in 2018 [Diploma]
  • 2015 Discovery Award for contribution to the extraordinary shift in the field of medicine [link]
  • 2010-2018 5x 3rd Prize of the Henneruv nadacni fond for outstanding journal publication
  • 2013 Rector's Prize for outstanding PhD thesis Acoustic Analysis of Voice and Speech Disorders in Parkinson’s Disease
  • 2011 European Federation of Neurological Societies Investigator Award Winner in Movement Disorders panel for the presentation:
    J. Rusz, R. Čmejla, H. Růžičková, J. Klempíř, V. Majerová, J. Picmausová, J. Roth, and E. Růžička. (2011). "Two-minute vocal test and acoustic analysis reveal voice and speech disorders in early untreated Parkinson's disease," in 15th congress of the European federation of neurological societies, Budapest, Hungary, vol. 18, supp. 2, p. 118. [abstract] [poster]
  • 2011 European Acoustic Association grant for young researchers for participating at the Forum Acusticum 2011 Congress for the presentation:
    J. Rusz, R. Čmejla, H. Růžičková, J. Klempíř, V. Majerová, J. Picmausová, J. Roth, and E. Růžička. (2011). "Acoustic markers of speech degradation in early untreated Parkinson's disease," in Proceedings of Forum Acusticum 2011. Aalborg, DK, 2725-2730. [PDF]
  • 2008 Dean's Prize for the diploma thesis Usage of simulation model of global human physiological functions as a background of e-learning teaching of critical care medicine

    Editorial Boards

  • (2013-2021) Logopedics Phoniatrics Vocology (Associate Editor) [web]
  • (2016-2017) SpringerPlus

    Conference Organization

  • 3rd Speech and Swallowing in Parkinson's Disease School , Prague, Czech Republic [2019]

    Invited Lectures

  • MDS-ES Allied Health Care in Movement Disorders , Prague, Czechia, 2023
  • Workshop on "New developments in assessment approaches, tools and data for motor speech disorders, Idiap Research Institute, Switzerland, 2023
  • EMBL-EBI Industry Programme workshop - Current practices in processing and analysing digital biomarker data 2022
  • 4rd MDS Speech and Swallowing in Parkinson’s Disease School [2021]
  • 13th Symposium on Movement Disorders Bern [2021]
  • 2nd Speech and Swallowing in Parkinson's Disease School [2018]
  • 11th International REM Sleep Behavior Disorder Study Group Meeting (RBD meeting) [2017]
  • Models and Analysis of Vocal Emissions for Biomedical Applications Workshop (MAVEBA) [2011] [2013]
  • European Neurological Society Congress (ENS) [2012]

    Research projects: principal investigator

  • 2024-2027 Czech Ministry of Health (MZČR) NW24-04-00211: Evolution of Speech Disorders in Parkinson's Disease
  • 2022-2025 Programme EXCELES, funded by the European Union – Next Generation EU LX22NPO5107: National institute for Neurological Research
  • 2021-2023 Czech Science Foundation (GAČR) 21-14216L: Reducing speech-related side-effects of deep brain stimulation in Parkinson's Disease via automated speech analysis
  • 2020-2023 Czech Ministry of Health (MZČR) NU20-08-00445: Smart Speech Biomarkers for Parkinson’s Disease and Other Synucleinopathies
  • 2019-2022 Czech Ministry of Health (MZČR) NV19-04-00120: Objective investigation of distinct speech phenotypes in newly diagnosed Parkinson's disease including effects of pharmacotherapy
  • 2017-2019 Michael J. Fox Foundation (MJFF) 12546: Automatic acoustic speech analysis and REM sleep behaviour disorder for detecting subjects at high risk for Parkinson's disease and other alpha-synucleinopathies
  • 2016-2018 Czech Science Foundation (GAČR) 16-03322S: Investigation of pathomechanisms responsible for speech and voice disorders in multiple sclerosis using new methods of objective acoustic analysis
  • 2015-2018 Czech Ministry of Health (MZČR) 15-28038A: Speech disorders and analysis of their mechanism in Parkinson's disease and other movement disorders



    Latest update: 23.07.2024

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    • Contact:
    Czech Technical University in Prague, Faculty of Electrical Engineering
    Department of Circuit Theory
    Technicka 2, 166 27 Prague 6, Czech Republic
    Phone: +420 2435 2236, e-mail: cmejla at fel.cvut.cz